Personalised Immunotherapy in Sepsis:
a precision medicine approach

Objectives

Design and conduct a large proof-of-concept randomised controlled trial to provide answers about the usefulness of personalised immunotherapy for sepsis patients.

Perform an integrated, multi-dimensional systems biology analysis of omics-based datasets, to identify biomarkers, clinical endotypes, and therapeutic targets needed for future precision medicine approaches.

Set up a new theranostics platform to help develop next-generation clinical trials through improved patient stratification and treatment allocation.

Integrate novel immunotherapeutic approaches into health systems through close collaboration with professional and patient organisations.